Partners and Programs

Enabling Innovation

Sage Bionetworks has collaborative programs for enabling biomedical research as well as an innovative training program to help fill the talent gap. Sage Bionetworks is also engaged in organizing important new public-private partnerships.

Center for Cancer Systems Biology

Sage Bionetworks recognizes that in addition to internal research projects and the Commons platform there is a parallel need for exporting advanced tools and expanding the set of people qualified to process and interpret highly complex data. We are addressing these needs through external partnerships and a specialized training initiative.

In order to train the next generation of real innovators in this highly interdisciplinary field, Sage Bionetworks believes that it is particularly important to bring together individuals who have a deep understanding of the math, physics, and statistics required to manipulate peta-byte sized data sets and individuals that have a working knowledge of the biology of human diseases. Experience has shown that it works well to merge the training of pairs of individuals. Specifically, training someone who is already a well-trained physicist to understand the biology better, while also enabling a well trained biologist to work with that well trained physicist, allows them together to become a very effective team.

In order to implement this training strategy, Sage Bionetworks has received a major grant from the National Cancer Institute's Integrative Cancer Genetics Program (ICBP) to create a new Center for Cancer Systems Biology (CCSB). The Sage Bionetworks Center For Cancer Systems Biology is a prestigious and competitive opportunity for scholars interested in working at the leading edge of the clinical-computational biology interface. Candidates are being recruited through solicitations to leading researchers as well as targeted advertising. The program includes mentoring with senior Sage researchers, independent research projects, classroom work as required and short "externships" with the Fred Hutchinson Cancer Research Center and other CCBPs. More information is available on the Sage CCSB page and the Sage Bionetworks Careers page. Each individually-tailored opportunity is designed to enable biologists, computational researchers and clinically-trained scientists to work and contribute at the cutting edge of integrative genomics and disease modeling as well as give them confidence and a track record of actively collaborating with multiple leaders in the field.

Washington Partners Program

Sage Bionetworks has created the Washington Partners Program (WPP) to provide biomedical researchers with strategic and cost-effective advanced genomics analysis capabilities.  Funded by the Washington Life Sciences Discovery Fund, the program is designed to accelerate academic and commercial research and improve healthcare outcomes in the state of Washington.  The program features active next-generation network biology collaborations between Sage Bionetworks scientists and select biomedical research teams. The goal is to rapidly develop internal partner capabilities by leveraging the analytical expertise of Sage Bionetworks' researchers and to achieve research and development goals with greater speed and success than is currently possible. 

More information is available in the Washington Partners Program Section.

Training environment

Sage Bionetworks leases space in the Arnold Building of the Fred Hutchinson Cancer Research Center and all Sage Bionetworks staff have full access to the excellent research resources (e.g., library and reference collection) and common areas (e.g., conference rooms) at the Center.

The Fred Hutchinson Cancer Research Center is an outstanding research environment with over 190 faculty members, almost 400 pre- and post-doctoral researchers and over 2,800 total staff. There is an extensive international seminar program and Sage Bionetworks scientists work closely with the FHCRC computational biology program as well as with other Public Health, Human Health and Basic Science collaborators. All Sage Bionetworks scientists have formal affiliate positions at FHCRC.

Seattle is a rich biomedical research community: Sage Bionetworks and FHCRC are located within two miles of the University of Washington, and its Medical Center, Seattle Biotechnology Research Institute (SBRI), the Institute for Systems Biology (ISB), Seattle Children's Hospital, the Program for Appropriate Health Technology (PATH) and the Benaroya Institute which continues to facilitate many productive interactions. Seattle has a number of biotech start-ups, pharma affiliates and IT companies with whom Sage interacts as well including Amgen, Zymogenetics, Calistoga and Microsoft.

Sage Bionetworks has an excellent high performance computational facility comprised of a 5,488 CPU core Linux cluster with over 40TB of online data storage capacity. The cluster consists of ~5,000 job slots with a combination of quad core Intel Xeons, 64bit single core Xeons and AMD dual core Opteron processors. One of the major components is an Isilon clustered file system with 36 nodes. Each node in the Isilon is attached to the cluster via gigabit Ethernet. This highly parallelized file system is very well suited to supporting systems biology and bioinformatics workflows and the cluster is well maintained through a partnership agreement with the University of Miami.

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